Cargando…

Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model

The ATP-gated P2X7 receptor is highly expressed in microglia and has been involved in diverse brain diseases. P2X7 effects were also described in neurons and astrocytes but its localisation and function in these cell types has been challenging to demonstrate in situ. BAC transgenic mouse lines have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramírez-Fernández, Antonio, Urbina-Treviño, Lidia, Conte, Giorgia, Alves, Mariana, Rissiek, Björn, Durner, Anna, Scalbert, Nicolas, Zhang, Jiong, Magnus, Tim, Koch-Nolte, Friedrich, Plesnila, Nikolaus, Deussing, Jan M., Engel, Tobias, Kopp, Robin, Nicke, Annette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669894/ https://www.ncbi.nlm.nih.gov/pubmed/33199725 http://dx.doi.org/10.1038/s41598-020-76428-0

Ejemplares similares

Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions
por: Wilmes, Maximilian, et al.
Publicado: (2022)

A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice
por: Er-Lukowiak, Marco, et al.
Publicado: (2020)

Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
por: Kaczmarek-Hajek, Karina, et al.
Publicado: (2018)

P2X7 Receptor-Related Genetic Mouse Models – Tools for Translational Research in Psychiatry
por: Urbina-Treviño, Lidia, et al.
Publicado: (2022)

Editorial: P2X7 as Common Therapeutic Target in Brain Diseases
por: Engel, Tobias, et al.
Publicado: (2021)

Characterization of a microglia-specific humanized P2X7 receptor knock-out mouse line: Implications for translational psychoneuroimmunology
por: Urbina Trevino, L., et al.
Publicado: (2022)

Improved ANAP incorporation and VCF analysis reveal details of P2X7 current facilitation and a limited conformational interplay between ATP binding and the intracellular ballast domain
por: Durner, Anna, et al.
Publicado: (2023)

P2X7 on Mouse T Cells: One Channel, Many Functions
por: Rissiek, Björn, et al.
Publicado: (2015)

Heteromeric assembly of P2X subunits
por: Saul, Anika, et al.
Publicado: (2013)

P2X7R antagonists in chronic stress-based depression models: a review
por: von Muecke-Heim, Iven-Alex, et al.
Publicado: (2021)

Effective targeting of microglial P2X7 following intracerebroventricular delivery of nanobodies and nanobody-encoding AAVs
por: Pinto-Espinoza, Carolina, et al.
Publicado: (2022)

BAC transgenic mice to study the expression of P2X2 and P2Y(1) receptors
por: Grohmann, Marcus, et al.
Publicado: (2021)

P2X7 Interactions and Signaling – Making Head or Tail of It
por: Kopp, Robin, et al.
Publicado: (2019)

New insights into P2X7 receptor regulation: Ca(2+)-calmodulin and GDP bind to the soluble P2X7 ballast domain
por: Sander, Simon, et al.
Publicado: (2022)

Astrocytes and Microglia Are Resistant to NAD(+)-Mediated Cell Death Along the ARTC2/P2X7 Axis
por: Rissiek, Björn, et al.
Publicado: (2020)

Animal Models for the Investigation of P2X7 Receptors
por: Sluyter, Ronald, et al.
Publicado: (2023)

BAC-Dkk3-EGFP Transgenic Mouse: An In Vivo Analytical Tool for Dkk3 Expression
por: Muranishi, Yuki, et al.
Publicado: (2012)

P2X4 and P2X7 are essential players in basal T cell activity and Ca(2+) signaling milliseconds after T cell activation
por: Brock, Valerie J., et al.
Publicado: (2022)

Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel
por: Schäfer, Waldemar, et al.
Publicado: (2022)

Molecular and functional properties of P2X receptors—recent progress and persisting challenges
por: Kaczmarek-Hájek, Karina, et al.
Publicado: (2012)

Generation and Characterization of Specific Monoclonal Antibodies and Nanobodies Directed Against the ATP-Gated Channel P2X4
por: Bergmann, Philine, et al.
Publicado: (2019)

Extracellular NAD(+) shapes the Foxp3(+) regulatory T cell compartment through the ART2–P2X7 pathway
por: Hubert, Sandra, et al.
Publicado: (2010)

Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation
por: Schwarz, Nicole, et al.
Publicado: (2012)

Detection measures for visual inspection of X-ray images of passenger baggage
por: Sterchi, Yanik, et al.
Publicado: (2019)

P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis
por: Zabala, Alazne, et al.
Publicado: (2018)

Progress report of experiment P7: $K^{-}p$ and $\bar{p}p$ x-rays
por: CERN. Geneva. Electronic Experiments Committee
Publicado: (1976)

Status report : status report and request for extension of P7 ($K^{-}$ -p and $\overline{p}$-p x-rays)
por: CERN. Geneva. Electronic Experiments Committee
Publicado: (1975)

Retrofitting the BAC cloning vector pBeloBAC11 by the insertion of a mutant loxP site
por: Coren, Jonathon S.
Publicado: (2017)

Progress report of experiment S151: $K^{-}p$ and $\bar{p}p$ x-rays
por: CERN. Geneva. Proton Synchrotron and Synchrocyclotron Committee
Publicado: (1976)

The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation
por: von Mücke-Heim, Iven-Alex, et al.
Publicado: (2023)

Update of P2X receptor properties and their pharmacology: IUPHAR Review 30
por: Illes, Peter, et al.
Publicado: (2020)

The Routledge handbook of deviant behaviour /
Publicado: (2011)

Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy
por: Conte, Giorgia, et al.
Publicado: (2021)

Comparative Analysis of P2X1, P2X2, P2X3, and P2X4 Receptor Subunits in Rat Nodose Ganglion Neurons
por: Wang, Lizhao, et al.
Publicado: (2014)

P2X7 receptor inhibition ameliorates ubiquitin–proteasome system dysfunction associated with Alzheimer’s disease
por: Bianchi, Carolina, et al.
Publicado: (2023)

Evaluation of eGFP expression in the ChAT-eGFP transgenic mouse brain
por: Gamage, Rashmi, et al.
Publicado: (2023)

EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions
por: Rodriguez-Alvarez, Marta, et al.
Publicado: (2020)

Mosaicism for r(X) and der(X)del(X)(p11.23)dup(X)(p11.21p11.22) provides insight into the possible mechanism of rearrangement
por: Shchelochkov, Oleg A, et al.
Publicado: (2008)

Features of emotion recognition in deviant adolescents
por: Abolonin, A., et al.
Publicado: (2021)

BAC-FISH refutes report of an 8p22–8p23.1 inversion or duplication in 8 patients with Kabuki syndrome
por: Kimberley, Kendra W, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_akqrm3b123oq1qfej1ak7eahnk