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Synthesis of purines and adenines containing the hexafluoroisopropyl group

Several new derivatives of adenine, purine, and theophylline containing the (CF(3))(2)CH group connected to a nitrogen atom of the imidazole ring were prepared by the reaction of 2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithietane (1) with the corresponding substrates, resulting in the selective alkyla...

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Detalles Bibliográficos
Autores principales: Petrov, Viacheslav, Dooley, Rebecca J, Marchione, Alexander A, Diaz, Elizabeth L, Clem, Brittany S, Marshall, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670113/
https://www.ncbi.nlm.nih.gov/pubmed/33224300
http://dx.doi.org/10.3762/bjoc.16.224