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Mucosal‐associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy‐related colitis in a pathology distinct from ulcerative colitis

The aim of this study was to investigate the pathogenesis of combination ipilimumab and nivolumab‐associated colitis (IN‐COL) by measuring gut‐derived and peripheral blood mononuclear cell (GMNC; PBMC) profiles. We studied GMNC and PBMC from patients with IN‐COL, IN‐treated with no adverse‐events (I...

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Detalles Bibliográficos
Autores principales: Sasson, S. C., Zaunders, J. J., Nahar, K., Munier, C. M. L., Fairfax, B. P., Olsson‐Brown, A., Jolly, C., Read, S. A., Ahlenstiel, G., Palendira, U., Scolyer, R. A., Carlino, M. S., Payne, M. J., Cheung, V. T. F., Gupta, T., Klenerman, P., Long, G. V., Brain, O., Menzies, A. M., Kelleher, A. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670140/
https://www.ncbi.nlm.nih.gov/pubmed/32734627
http://dx.doi.org/10.1111/cei.13502