Cargando…

ZG02 Improved Hepatic Glucose Metabolism and Insulin Sensitivity via Activation of AMPK/Sirt1 Signaling Pathways in a High-fat Diet/Streptozotocin-induced Type 2 Diabetes Model

PURPOSE: The aim of the present study was to investigate the hypoglycemic activity and potential mechanism of tetrahydrocarbazole derivatives ZG02 in high-fat diet/streptozotocin-induced type 2 diabetes model. METHODS: C57BL/6 mice (n=30) were randomly assigned to three groups: control group (n=10)...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhou, Bo, Wen, Min, Hu, Mi, Peng, Jin-Gang, Wang, Ying, Fan, Lin-Lin, Tang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670175/
https://www.ncbi.nlm.nih.gov/pubmed/33209046
http://dx.doi.org/10.2147/DMSO.S275145