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ZG02 Improved Hepatic Glucose Metabolism and Insulin Sensitivity via Activation of AMPK/Sirt1 Signaling Pathways in a High-fat Diet/Streptozotocin-induced Type 2 Diabetes Model
PURPOSE: The aim of the present study was to investigate the hypoglycemic activity and potential mechanism of tetrahydrocarbazole derivatives ZG02 in high-fat diet/streptozotocin-induced type 2 diabetes model. METHODS: C57BL/6 mice (n=30) were randomly assigned to three groups: control group (n=10)...
Autores principales: | Zhang, Yi, Zhou, Bo, Wen, Min, Hu, Mi, Peng, Jin-Gang, Wang, Ying, Fan, Lin-Lin, Tang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670175/ https://www.ncbi.nlm.nih.gov/pubmed/33209046 http://dx.doi.org/10.2147/DMSO.S275145 |
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