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Model-based optimization of the primary drying phase of oral lyophilizates
Oral lyophilizates also called orally disintegrating tablets (ODTs) are a patient friendly and convenient dosage form. They are manufactured by dosing a suspension in blister cups and subsequently freeze-drying these blisters to achieve porous tablets that disintegrate quickly (< 10 s) when place...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670193/ https://www.ncbi.nlm.nih.gov/pubmed/33235992 http://dx.doi.org/10.1016/j.ijpx.2020.100057 |