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Model-based optimization of the primary drying phase of oral lyophilizates

Oral lyophilizates also called orally disintegrating tablets (ODTs) are a patient friendly and convenient dosage form. They are manufactured by dosing a suspension in blister cups and subsequently freeze-drying these blisters to achieve porous tablets that disintegrate quickly (< 10 s) when place...

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Detalles Bibliográficos
Autores principales: Vanbillemont, Brecht, De Beer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670193/
https://www.ncbi.nlm.nih.gov/pubmed/33235992
http://dx.doi.org/10.1016/j.ijpx.2020.100057