Global transcriptomic profiling of microcystin-LR or -RR treated hepatocytes (HepaRG)

The canonical mode of action (MOA) of microcystins (MC) is the inhibition of protein phosphatases, but complete characterization of toxicity pathways is lacking. The existence of over 200 MC congeners complicates risk estimates worldwide. This work employed RNA-seq to provide an unbiased and compreh...

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Detalles Bibliográficos
Autores principales: Biales, Adam D., Bencic, David C., Flick, Robert W., Delacruz, Armah, Gordon, Denise A., Huang, Weichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670210/
https://www.ncbi.nlm.nih.gov/pubmed/33235993
http://dx.doi.org/10.1016/j.toxcx.2020.100060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670210/
https://www.ncbi.nlm.nih.gov/pubmed/33235993
http://dx.doi.org/10.1016/j.toxcx.2020.100060

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