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Global transcriptomic profiling of microcystin-LR or -RR treated hepatocytes (HepaRG)
The canonical mode of action (MOA) of microcystins (MC) is the inhibition of protein phosphatases, but complete characterization of toxicity pathways is lacking. The existence of over 200 MC congeners complicates risk estimates worldwide. This work employed RNA-seq to provide an unbiased and compreh...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670210/ https://www.ncbi.nlm.nih.gov/pubmed/33235993 http://dx.doi.org/10.1016/j.toxcx.2020.100060 |