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Toll-like receptor 4 regulates intestinal fibrosis via cytokine expression and epithelial-mesenchymal transition

Intestinal fibrosis induced by chronic and recurrent colitis, which is exacerbated by bowel stenosis, stricture, and obstruction, is challenging to treat. Toll-like receptor 4 (TLR4) stimulates innate and acquired immunity in response to specific microbial components, but the role of TLR4 in intesti...

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Detalles Bibliográficos
Autores principales: Jun, Yu Kyung, Kwon, So Hyun, Yoon, Hee Tae, Park, Hyunsun, Soh, Hosim, Lee, Hyun Jung, Im, Jong Pil, Kim, Joo Sung, Kim, Ji Won, Koh, Seong-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670421/
https://www.ncbi.nlm.nih.gov/pubmed/33199767
http://dx.doi.org/10.1038/s41598-020-76880-y