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TZM-gfp cells: a tractable fluorescent tool for analysis of rare and early HIV-1 infection

Here we describe TZM-gfp, a novel HIV-1 reporter cell derived from the same parental clone JC.53, used previously to generate the widely-utilized indicator cell line TZM-bl. We re-engineered JC.53 cells to express GFP under regulation of HIV Tat and Rev. We characterize the new reporter cell line to...

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Detalles Bibliográficos
Autores principales: Gludish, David W., Boliar, Saikat, Caldwell, Shannon, Tembo, Dumizulu L., Chimbayo, Elizabeth T., Jambo, Kondwani C., Mwandumba, Henry C., Russell, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670428/
https://www.ncbi.nlm.nih.gov/pubmed/33199722
http://dx.doi.org/10.1038/s41598-020-76422-6