Investigation of COSMO-SAC model for solubility and cocrystal formation of pharmaceutical compounds

In this study, a predictive model named COSMO-SAC was investigated in solid/liquid equilibria for pharmaceutical compounds. The examined properties were the solubility of drug in the pure and mixed solvents, octanol/water partition coefficient, and cocrystal formation. The results of the original CO...

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Detalles Bibliográficos
Autores principales: Mahmoudabadi, Samane Zarei, Pazuki, Gholamreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670437/
https://www.ncbi.nlm.nih.gov/pubmed/33199834
http://dx.doi.org/10.1038/s41598-020-76986-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670437/
https://www.ncbi.nlm.nih.gov/pubmed/33199834
http://dx.doi.org/10.1038/s41598-020-76986-3

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