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Investigation of COSMO-SAC model for solubility and cocrystal formation of pharmaceutical compounds
In this study, a predictive model named COSMO-SAC was investigated in solid/liquid equilibria for pharmaceutical compounds. The examined properties were the solubility of drug in the pure and mixed solvents, octanol/water partition coefficient, and cocrystal formation. The results of the original CO...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670437/ https://www.ncbi.nlm.nih.gov/pubmed/33199834 http://dx.doi.org/10.1038/s41598-020-76986-3 |