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Tetrahydrobiopterin prevents chronic ischemia-related lower urinary tract dysfunction through the maintenance of nitric oxide bioavailability

This study aimed to investigate the influence of chronic ischemia on nitric oxide biosynthesis in the bladder and the effect of administering tetrahydrobiopterin (BH4), a cofactor for endothelial nitric oxide synthase (eNOS), on chronic ischemia-related lower urinary tract dysfunction (LUTD). This s...

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Detalles Bibliográficos
Autores principales: Akaihata, Hidenori, Hata, Junya, Tanji, Ryo, Honda-Takinami, Ruriko, Matsuoka, Kanako, Sato, Yuichi, Kataoka, Masao, Ogawa, Soichiro, Kojima, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670448/
https://www.ncbi.nlm.nih.gov/pubmed/33199757
http://dx.doi.org/10.1038/s41598-020-76948-9