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Tetrahydrobiopterin prevents chronic ischemia-related lower urinary tract dysfunction through the maintenance of nitric oxide bioavailability
This study aimed to investigate the influence of chronic ischemia on nitric oxide biosynthesis in the bladder and the effect of administering tetrahydrobiopterin (BH4), a cofactor for endothelial nitric oxide synthase (eNOS), on chronic ischemia-related lower urinary tract dysfunction (LUTD). This s...
Autores principales: | Akaihata, Hidenori, Hata, Junya, Tanji, Ryo, Honda-Takinami, Ruriko, Matsuoka, Kanako, Sato, Yuichi, Kataoka, Masao, Ogawa, Soichiro, Kojima, Yoshiyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670448/ https://www.ncbi.nlm.nih.gov/pubmed/33199757 http://dx.doi.org/10.1038/s41598-020-76948-9 |
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