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Cerebral Blood Flow–Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia‐Induced Cardiac Arrest in Rats

BACKGROUND: In most post–cardiac arrest patients, the autoregulation mechanism of cerebral blood flow (CBF) is dysregulated. We examined whether recovery of CBF by adjusting mean arterial pressure mitigates post–cardiac arrest neuronal damage. METHODS AND RESULTS: Wistar rats that underwent 8‐minute...

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Detalles Bibliográficos
Autores principales: Wang, Chih‐Hung, Chang, Wei‐Tien, Huang, Chien‐Hua, Tsai, Min‐Shan, Liu, Shing‐Hwa, Chen, Wen‐Jone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670514/
https://www.ncbi.nlm.nih.gov/pubmed/32552439
http://dx.doi.org/10.1161/JAHA.120.016513