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Pathological Role of Receptor for Advanced Glycation End Products in Calcified Aortic Valve Stenosis

BACKGROUND: Aortic stenosis (AS) is highly prevalent in patients with atherosclerotic cardiovascular disease. Advanced glycation end products (AGEs) and the receptor for AGEs (RAGE) play a pivotal role for vascular calcification in atherosclerosis. We hypothesize that the AGEs–RAGE axis could also b...

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Detalles Bibliográficos
Autores principales: Saku, Kosuke, Tahara, Nobuhiro, Takaseya, Tohru, Otsuka, Hiroyuki, Takagi, Kazuyoshi, Shojima, Takahiro, Shintani, Yusuke, Zaima, Yasuyuki, Kikusaki, Satoshi, Fukuda, Tomofumi, Oryoji, Atsunobu, Nishino, Yuri, Matsui, Takanori, Kakuma, Tatsuyuki, Akiba, Jun, Fukumoto, Yoshihiro, Yamagishi, Sho‐ichi, Tanaka, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670521/
https://www.ncbi.nlm.nih.gov/pubmed/32552251
http://dx.doi.org/10.1161/JAHA.119.015261