Cargando…

Sacubitril/Valsartan Improves Cardiac Function and Decreases Myocardial Fibrosis Via Downregulation of Exosomal miR‐181a in a Rodent Chronic Myocardial Infarction Model

BACKGROUND: Exosomes are small extracellular vesicles that function as intercellular messengers and effectors. Exosomal cargo contains regulatory small molecules, including miRNAs, mRNAs, lncRNAs, and small peptides that can be modulated by different pathological stimuli to the cells. One of the mai...

Descripción completa

Detalles Bibliográficos
Autores principales: Vaskova, Evgeniya, Ikeda, Gentaro, Tada, Yuko, Wahlquist, Christine, Mercola, Marc, Yang, Phillip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670523/
https://www.ncbi.nlm.nih.gov/pubmed/32538237
http://dx.doi.org/10.1161/JAHA.119.015640