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Angiotensin Receptor‐Neprilysin Inhibition Attenuates Right Ventricular Remodeling in Pulmonary Hypertension

BACKGROUND: Pulmonary hypertension (PH) results in increased right ventricular (RV) afterload and ventricular remodeling. Sacubitril/valsartan (sac/val) is a dual acting drug, composed of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan, that has shown promising out...

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Detalles Bibliográficos
Autores principales: Sharifi Kia, Danial, Benza, Evan, Bachman, Timothy N., Tushak, Claire, Kim, Kang, Simon, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670537/
https://www.ncbi.nlm.nih.gov/pubmed/32552157
http://dx.doi.org/10.1161/JAHA.119.015708