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Electrochemically detecting DNA methylation in the EN1 gene promoter: implications for understanding ageing and disease

There is a growing need for biomarkers which predict age-onset pathology. Although this is challenging, the methylome offers significant potential. Cancer is associated with the hypermethylation of many gene promoters, among which are developmental genes. Evolutionary theory suggests developmental g...

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Detalles Bibliográficos
Autores principales: Morgan, Amy E., Acutt, Katie D., Mc Auley, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670582/
https://www.ncbi.nlm.nih.gov/pubmed/33135722
http://dx.doi.org/10.1042/BSR20202571