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Circular RNA MCTP2 inhibits cisplatin resistance in gastric cancer by miR-99a-5p-mediated induction of MTMR3 expression

BACKGROUND: Cisplatin (CDDP) is the first-line chemotherapy for gastric cancer (GC). The poor prognosis of GC patients is partially due to the development of CDDP resistance. Circular RNAs (circRNAs) are a subclass of noncoding RNAs that function as microRNA (miRNA) sponges. The role of circRNAs in...

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Detalles Bibliográficos
Autores principales: Sun, Guangli, Li, Zheng, He, Zhongyuan, Wang, Weizhi, Wang, Sen, Zhang, Xing, Cao, Jiacheng, Xu, Penghui, Wang, Haixiao, Huang, Xiaoxu, Xia, Yiwen, Lv, Jialun, Xuan, Zhe, Jiang, Tianlu, Fang, Lang, Yang, Jing, Zhang, Diancai, Xu, Hao, Xu, Zekuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670601/
https://www.ncbi.nlm.nih.gov/pubmed/33198772
http://dx.doi.org/10.1186/s13046-020-01758-w