EZH2 promotes the expression of LPA1 by mediating microRNA-139 promoter methylation to accelerate the development of ovarian cancer

BACKGROUND: It has been known that ovarian cancer (OC) is a leading cause for women mortality globally. We aimed to analyze the underlying mechanism supporting that enhancer of zeste homolog 2 (EZH2) affected the development of OC via the involvement of microRNA-139 (miR-139)/transforming growth fac...

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Detalles Bibliográficos
Autores principales: Wu, Dongbo, Wu, Fanglan, Li, Birong, Huang, Wei, Wang, Donglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670614/
https://www.ncbi.nlm.nih.gov/pubmed/33292225
http://dx.doi.org/10.1186/s12935-020-01622-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670614/
https://www.ncbi.nlm.nih.gov/pubmed/33292225
http://dx.doi.org/10.1186/s12935-020-01622-z

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