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EZH2 promotes the expression of LPA1 by mediating microRNA-139 promoter methylation to accelerate the development of ovarian cancer
BACKGROUND: It has been known that ovarian cancer (OC) is a leading cause for women mortality globally. We aimed to analyze the underlying mechanism supporting that enhancer of zeste homolog 2 (EZH2) affected the development of OC via the involvement of microRNA-139 (miR-139)/transforming growth fac...
Autores principales: | Wu, Dongbo, Wu, Fanglan, Li, Birong, Huang, Wei, Wang, Donglian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670614/ https://www.ncbi.nlm.nih.gov/pubmed/33292225 http://dx.doi.org/10.1186/s12935-020-01622-z |
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