Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats

BACKGROUND: This study was aimed to investigate the therapeutic effects and potential mechanism of higenamine combined with [6]-gingerol (HG/[6]-GR) against doxorubicin (DOX)—induced chronic heart failure (CHF) in rats. MATERIALS AND METHODS: Therapeutic effects of HG/[6]-GR on hemodynamics indices,...

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Detalles Bibliográficos
Autores principales: Wen, Jianxia, Ma, Xiao, Niu, Ming, Hao, Junjie, Huang, Ying, Wang, Ruilin, Li, Ruisheng, Wang, Jian, Zhao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670783/
https://www.ncbi.nlm.nih.gov/pubmed/33292391
http://dx.doi.org/10.1186/s13020-020-00403-0