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C3 amino-substituted chalcone derivative with selective adenosine rA(1) receptor affinity in the micromolar range
ABSTRACT: To identify novel adenosine receptor (AR) ligands based on the chalcone scaffold, herein the synthesis, characterization and in vitro and in silico evaluation of 33 chalcones (15–36 and 37–41) and structurally related compounds (42–47) are reported. These compounds were characterized by ra...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670844/ https://www.ncbi.nlm.nih.gov/pubmed/33223599 http://dx.doi.org/10.1007/s11696-020-01414-9 |