Predictive and Prognostic Value of DNA Damage Response Associated Kinases in Solid Tumors

Dysfunctional DNA repair with subsequent genome instability and high mutational burden represents a major hallmark of cancer. In established malignant tumors, increased DNA repair capacity mediates resistance to DNA-damaging therapeutics, including cytotoxic drugs, radiotherapy, and selected small m...

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Detalles Bibliográficos
Autores principales: Gachechiladze, Mariam, Skarda, Josef, Bouchalova, Katerina, Soltermann, Alex, Joerger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670868/
https://www.ncbi.nlm.nih.gov/pubmed/33224881
http://dx.doi.org/10.3389/fonc.2020.581217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670868/
https://www.ncbi.nlm.nih.gov/pubmed/33224881
http://dx.doi.org/10.3389/fonc.2020.581217

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