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Predictive and Prognostic Value of DNA Damage Response Associated Kinases in Solid Tumors

Dysfunctional DNA repair with subsequent genome instability and high mutational burden represents a major hallmark of cancer. In established malignant tumors, increased DNA repair capacity mediates resistance to DNA-damaging therapeutics, including cytotoxic drugs, radiotherapy, and selected small m...

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Detalles Bibliográficos
Autores principales:	Gachechiladze, Mariam, Skarda, Josef, Bouchalova, Katerina, Soltermann, Alex, Joerger, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670868/ https://www.ncbi.nlm.nih.gov/pubmed/33224881 http://dx.doi.org/10.3389/fonc.2020.581217

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