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Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

SARS-CoV-2 infection has led to a global health crisis, and yet our understanding of the disease and potential treatment options remains limited. The infection occurs through binding of the virus with angiotensin converting enzyme 2 (ACE2) on the cell membrane. Here, we established a screening strat...

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Detalles Bibliográficos
Autores principales: Samuel, Ryan M., Majd, Homa, Richter, Mikayla N., Ghazizadeh, Zaniar, Zekavat, Seyedeh Maryam, Navickas, Albertas, Ramirez, Jonathan T., Asgharian, Hosseinali, Simoneau, Camille R., Bonser, Luke R., Koh, Kyung Duk, Garcia-Knight, Miguel, Tassetto, Michel, Sunshine, Sara, Farahvashi, Sina, Kalantari, Ali, Liu, Wei, Andino, Raul, Zhao, Hongyu, Natarajan, Pradeep, Erle, David J., Ott, Melanie, Goodarzi, Hani, Fattahi, Faranak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670929/
https://www.ncbi.nlm.nih.gov/pubmed/33232663
http://dx.doi.org/10.1016/j.stem.2020.11.009