Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response

Current smoking is associated with increased risk of severe COVID-19, but it is not clear how cigarette smoke (CS) exposure affects SARS-CoV-2 airway cell infection. We directly exposed air-liquid interface (ALI) cultures derived from primary human nonsmoker airway basal stem cells (ABSCs) to short...

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Detalles Bibliográficos
Autores principales: Purkayastha, Arunima, Sen, Chandani, Garcia, Gustavo, Langerman, Justin, Shia, David W., Meneses, Luisa K., Vijayaraj, Preethi, Durra, Abdo, Koloff, Caroline R., Freund, Delilah R., Chi, Justin, Rickabaugh, Tammy M., Mulay, Apoorva, Konda, Bindu, Sim, Myung S., Stripp, Barry R., Plath, Kathrin, Arumugaswami, Vaithilingaraja, Gomperts, Brigitte N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670932/
https://www.ncbi.nlm.nih.gov/pubmed/33259798
http://dx.doi.org/10.1016/j.stem.2020.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670932/
https://www.ncbi.nlm.nih.gov/pubmed/33259798
http://dx.doi.org/10.1016/j.stem.2020.11.010

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