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A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2
Vaccines and antiviral agents are in urgent need to stop the COVID-19 pandemic. To facilitate antiviral screening against SARS-CoV-2 without requirement for high biosafety level facility, we developed a bacterial artificial chromosome (BAC)-vectored replicon of SARS-CoV-2, nCoV-SH01 strain, in which...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670965/ https://www.ncbi.nlm.nih.gov/pubmed/33217430 http://dx.doi.org/10.1016/j.antiviral.2020.104974 |