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A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2

Vaccines and antiviral agents are in urgent need to stop the COVID-19 pandemic. To facilitate antiviral screening against SARS-CoV-2 without requirement for high biosafety level facility, we developed a bacterial artificial chromosome (BAC)-vectored replicon of SARS-CoV-2, nCoV-SH01 strain, in which...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Song, Wuhui, Chen, Shuiye, Yuan, Zhenghong, Yi, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670965/
https://www.ncbi.nlm.nih.gov/pubmed/33217430
http://dx.doi.org/10.1016/j.antiviral.2020.104974