Are redox changes a critical switch for mitotic progression?

Cell-cycle dependent redox changes result in increased protein oxidation in mitotic cells. We show that oxidative modifications of a conserved cysteine residue within Aurora A kinase (AURKA) can promote its activation during mitosis. Targeting redox-sensitive cysteine residues within AURKA may lead...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Daniel C., Joukov, Vladimir, Yaffe, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Author’s Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670999/
https://www.ncbi.nlm.nih.gov/pubmed/33235921
http://dx.doi.org/10.1080/23723556.2020.1832419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670999/
https://www.ncbi.nlm.nih.gov/pubmed/33235921
http://dx.doi.org/10.1080/23723556.2020.1832419

Ejemplares similares