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Epigenetic suppression of FBXL7 promotes metastasis

Epigenetic reprogramming is emerging as a key mechanism for metastasis development. Our study identified a novel regulatory mechanism whereby promoter methylation-mediated epigenetic silencing of the gene encoding the ubiquitin ligase subunit F-box/LRR-repeat protein 7 (FBXL7) induces accumulation o...

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Detalles Bibliográficos
Autores principales: Moro, Loredana, Pagano, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671034/
https://www.ncbi.nlm.nih.gov/pubmed/33235922
http://dx.doi.org/10.1080/23723556.2020.1833698