Cargando…
Epigenetic suppression of FBXL7 promotes metastasis
Epigenetic reprogramming is emerging as a key mechanism for metastasis development. Our study identified a novel regulatory mechanism whereby promoter methylation-mediated epigenetic silencing of the gene encoding the ubiquitin ligase subunit F-box/LRR-repeat protein 7 (FBXL7) induces accumulation o...
Autores principales: | Moro, Loredana, Pagano, Michele |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671034/ https://www.ncbi.nlm.nih.gov/pubmed/33235922 http://dx.doi.org/10.1080/23723556.2020.1833698 |
Ejemplares similares
-
Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis
por: Moro, Loredana, et al.
Publicado: (2020) -
FSTL1 promotes bone metastasis by causing immune dysfunction
por: Kudo-Saito, Chie
Publicado: (2013) -
TAM macrophages promote growth and metastasis within the cancer ecosystem
por: Zarif, Jelani C, et al.
Publicado: (2014) -
RhoGDI2 suppresses bladder cancer metastasis via reduction of inflammation in the tumor microenvironment
por: Said, Neveen, et al.
Publicado: (2012) -
HIF-1 suppresses lipid catabolism to promote cancer progression
por: Zhang, Huafeng
Publicado: (2015)