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Cytoplasmic MYC is an anti-necroptotic protein

Cancer cells are often resistant to necroptosis as well as apotosis, but the underlying mechanisms are not fully understood. We recently revealed an important crosstalk between MYC, a potent oncogene, and receptor-interacting protein kinase 3 (RIPK3), a pivotal factor in inducing necroptosis. Mechan...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Woo, Seong, Daehyeon, Song, Jaewhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671064/
https://www.ncbi.nlm.nih.gov/pubmed/33235915
http://dx.doi.org/10.1080/23723556.2020.1817697