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Proline-based organocatalyst-mediated asymmetric aldol reaction of acetone with substituted aromatic aldehydes: an experimental and theoretical study

This work involves a facile synthesis of three (S) -proline-based organocatalysts with C2 symmetry and their effects in enantioselective aldol reaction of acetone with substituted aromatic aldehydes. Moderate enantioselectivities (up to 61% ee) were obtained depending on the nature of the substituen...

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Detalles Bibliográficos
Autores principales: ARSLAN, Nevin, ERCAN, Selami, PİRİNÇÇİOĞLU, Necmettin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671204/
https://www.ncbi.nlm.nih.gov/pubmed/33488161
http://dx.doi.org/10.3906/kim-1908-3