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The single nucleotide β -arrestin2 variant, A248T, resembles dynamical properties of activated arrestin
β -arrestins are responsible for termination of G protein-coupled receptor (GPCR)-mediated signaling. Association of single nucleotide variants with onset of crucial diseases has made this protein family hot targets in the field of GPCR-mediated pharmacology. However, impact of these mutations on fu...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Scientific and Technological Research Council of Turkey
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671214/ https://www.ncbi.nlm.nih.gov/pubmed/33488166 http://dx.doi.org/10.3906/kim-1910-46 |