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The single nucleotide β -arrestin2 variant, A248T, resembles dynamical properties of activated arrestin

β -arrestins are responsible for termination of G protein-coupled receptor (GPCR)-mediated signaling. Association of single nucleotide variants with onset of crucial diseases has made this protein family hot targets in the field of GPCR-mediated pharmacology. However, impact of these mutations on fu...

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Detalles Bibliográficos
Autor principal: ŞENSOY, Özge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671214/
https://www.ncbi.nlm.nih.gov/pubmed/33488166
http://dx.doi.org/10.3906/kim-1910-46