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Critical length in long-read resequencing

Long-read sequencing has substantial advantages for structural variant discovery and phasing of variants compared to short-read technologies, but the required and optimal read length has not been assessed. In this work, we used long reads simulated from human genomes and evaluated structural variant...

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Detalles Bibliográficos
Autores principales: De Coster, Wouter, Strazisar, Mojca, De Rijk, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671308/
https://www.ncbi.nlm.nih.gov/pubmed/33575574
http://dx.doi.org/10.1093/nargab/lqz027