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On the prediction of DNA-binding preferences of C2H2-ZF domains using structural models: application on human CTCF

Cis2-His2 zinc finger (C2H2-ZF) proteins are the largest family of transcription factors in human and higher metazoans. To date, the DNA-binding preferences of many members of this family remain unknown. We have developed a computational method to predict their DNA-binding preferences. We have compu...

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Detalles Bibliográficos
Autores principales: Meseguer, Alberto, Årman, Filip, Fornes, Oriol, Molina-Fernández, Ruben, Bonet, Jaume, Fernandez-Fuentes, Narcis, Oliva, Baldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671317/
https://www.ncbi.nlm.nih.gov/pubmed/33575598
http://dx.doi.org/10.1093/nargab/lqaa046