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Accelerating phylogeny-aware alignment with indel evolution using short time Fourier transform

Recently we presented a frequentist dynamic programming (DP) approach for multiple sequence alignment based on the explicit model of indel evolution Poisson Indel Process (PIP). This phylogeny-aware approach produces evolutionary meaningful gap patterns and is robust to the ‘over-alignment’ bias. De...

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Detalles Bibliográficos
Autores principales: Maiolo, Massimo, Ulzega, Simone, Gil, Manuel, Anisimova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671320/
https://www.ncbi.nlm.nih.gov/pubmed/33575636
http://dx.doi.org/10.1093/nargab/lqaa092