Depletion of erythropoietic miR-486-5p and miR-451a improves detectability of rare microRNAs in peripheral blood-derived small RNA sequencing libraries

Erythroid-specific miR-451a and miR-486-5p are two of the most dominant microRNAs (miRNAs) in human peripheral blood. In small RNA sequencing libraries, their overabundance reduces diversity as well as complexity and consequently causes negative effects such as missing detectability and inaccurate q...

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Detalles Bibliográficos
Autores principales: Juzenas, Simonas, Lindqvist, Carl M, Ito, Go, Dolshanskaya, Yewgenia, Halfvarson, Jonas, Franke, Andre, Hemmrich-Stanisak, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methart
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671325/
https://www.ncbi.nlm.nih.gov/pubmed/33575555
http://dx.doi.org/10.1093/nargab/lqaa008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671325/
https://www.ncbi.nlm.nih.gov/pubmed/33575555
http://dx.doi.org/10.1093/nargab/lqaa008

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