Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank cohort

The HLA genes, the most polymorphic genes in the human genome, constitute the strongest single genetic susceptibility factor for autoimmune diseases, transplantation alloimmunity and infections. HLA imputation via statistical inference of alleles based on single-nucleotide polymorphisms (SNPs) in li...

Descripción completa

Detalles Bibliográficos
Autores principales: Ritari, Jarmo, Hyvärinen, Kati, Clancy, Jonna, Partanen, Jukka, Koskela, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671345/
https://www.ncbi.nlm.nih.gov/pubmed/33575586
http://dx.doi.org/10.1093/nargab/lqaa030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671345/
https://www.ncbi.nlm.nih.gov/pubmed/33575586
http://dx.doi.org/10.1093/nargab/lqaa030

Ejemplares similares