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Associating divergent lncRNAs with target genes by integrating genome sequence, gene expression and chromatin accessibility data
Recent RNA knockdown experiments revealed that a dozen divergent long noncoding RNAs (lncRNAs) positively regulate the transcription of genes in cis. Here, to understand the regulatory mechanism of divergent lncRNAs, we proposed a computational model IRDL (Identify the Regulatory Divergent LncRNAs)...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671357/ https://www.ncbi.nlm.nih.gov/pubmed/33575579 http://dx.doi.org/10.1093/nargab/lqaa019 |