Associating divergent lncRNAs with target genes by integrating genome sequence, gene expression and chromatin accessibility data

Recent RNA knockdown experiments revealed that a dozen divergent long noncoding RNAs (lncRNAs) positively regulate the transcription of genes in cis. Here, to understand the regulatory mechanism of divergent lncRNAs, we proposed a computational model IRDL (Identify the Regulatory Divergent LncRNAs)...

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Detalles Bibliográficos
Autores principales: Wang, Yongcui, Chen, Shilong, Li, Wenran, Jiang, Rui, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671357/
https://www.ncbi.nlm.nih.gov/pubmed/33575579
http://dx.doi.org/10.1093/nargab/lqaa019

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