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Dimensionality reduction for single cell RNA sequencing data using constrained robust non-negative matrix factorization
Single cell RNA-sequencing (scRNA-seq) technology, a powerful tool for analyzing the entire transcriptome at single cell level, is receiving increasing research attention. The presence of dropouts is an important characteristic of scRNA-seq data that may affect the performance of downstream analyses...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671375/ https://www.ncbi.nlm.nih.gov/pubmed/33575614 http://dx.doi.org/10.1093/nargab/lqaa064 |