An empirical bayesian approach for testing gene expression fold change and its application in detecting global dosage effects

We are motivated by biological studies intended to understand global gene expression fold change. Biologists have generally adopted a fixed cutoff to determine the significance of fold changes in gene expression studies (e.g. by using an observed fold change equal to two as a fixed threshold). Scien...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Zhenxing, Cui, Ying, Shi, Xiaowen, Birchler, James A, Albizua, Igor, Sherman, Stephanie L, Qin, Zhaohui S, Ji, Tieming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671412/
https://www.ncbi.nlm.nih.gov/pubmed/33575620
http://dx.doi.org/10.1093/nargab/lqaa072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671412/
https://www.ncbi.nlm.nih.gov/pubmed/33575620
http://dx.doi.org/10.1093/nargab/lqaa072

Ejemplares similares