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An empirical bayesian approach for testing gene expression fold change and its application in detecting global dosage effects
We are motivated by biological studies intended to understand global gene expression fold change. Biologists have generally adopted a fixed cutoff to determine the significance of fold changes in gene expression studies (e.g. by using an observed fold change equal to two as a fixed threshold). Scien...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671412/ https://www.ncbi.nlm.nih.gov/pubmed/33575620 http://dx.doi.org/10.1093/nargab/lqaa072 |