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Counts: an outstanding challenge for log-ratio analysis of compositional data in the molecular biosciences

Thanks to sequencing technology, modern molecular bioscience datasets are often compositions of counts, e.g. counts of amplicons, mRNAs, etc. While there is growing appreciation that compositional data need special analysis and interpretation, less well understood is the discrete nature of these cou...

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Detalles Bibliográficos
Autores principales: Lovell, David R, Chua, Xin-Yi, McGrath, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671413/
https://www.ncbi.nlm.nih.gov/pubmed/33575593
http://dx.doi.org/10.1093/nargab/lqaa040