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Counts: an outstanding challenge for log-ratio analysis of compositional data in the molecular biosciences
Thanks to sequencing technology, modern molecular bioscience datasets are often compositions of counts, e.g. counts of amplicons, mRNAs, etc. While there is growing appreciation that compositional data need special analysis and interpretation, less well understood is the discrete nature of these cou...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671413/ https://www.ncbi.nlm.nih.gov/pubmed/33575593 http://dx.doi.org/10.1093/nargab/lqaa040 |