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PHi-C: deciphering Hi-C data into polymer dynamics

Genomes are spatiotemporally organized within the cell nucleus. Genome-wide chromosome conformation capture (Hi-C) technologies have uncovered the 3D genome organization. Furthermore, live-cell imaging experiments have revealed that genomes are functional in 4D. Although computational modeling metho...

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Detalles Bibliográficos
Autores principales: Shinkai, Soya, Nakagawa, Masaki, Sugawara, Takeshi, Togashi, Yuichi, Ochiai, Hiroshi, Nakato, Ryuichiro, Taniguchi, Yuichi, Onami, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671433/
https://www.ncbi.nlm.nih.gov/pubmed/33575580
http://dx.doi.org/10.1093/nargab/lqaa020