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Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibroblasts by Activating the Nrf2/HO-1 Signaling Pathway

PURPOSE: Periodontitis is a major chronic oral disease that is accelerated by activation of the NLRP3 inflammasome and the resulting pyroptosis. According to recent studies, active vitamin D and its analogs have been reported to have great anti-inflammatory effects. However, the anti-inflammatory me...

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Detalles Bibliográficos
Autores principales: Huang, Cancan, Zhang, Chaotao, Yang, Panpan, Chao, Rui, Yue, Ziqi, Li, Congshan, Guo, Jie, Li, Minqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671541/
https://www.ncbi.nlm.nih.gov/pubmed/33223823
http://dx.doi.org/10.2147/DDDT.S269223