Cargando…

G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus

Thyroid hormone (T3) inhibits thyrotropin-releasing hormone (TRH) synthesis in the hypothalamic paraventricular nucleus (PVN). Although the T3 receptor (TR) β2 is known to mediate the negative regulation of the prepro-TRH gene, its molecular mechanism remains unknown. Our previous studies on the T3-...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuroda, Go, Sasaki, Shigekazu, Matsushita, Akio, Ohba, Kenji, Sakai, Yuki, Shinkai, Shinsuke, Nakamura, Hiroko Misawa, Yamagishi, Satoru, Sato, Kohji, Hirahara, Naoko, Oki, Yutaka, Ito, Masahiko, Suzuki, Tetsuro, Suda, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671546/
https://www.ncbi.nlm.nih.gov/pubmed/33201916
http://dx.doi.org/10.1371/journal.pone.0242380