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SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight from a low-resolution technique
A significant problem in biological X-ray crystallography is the radiation chemistry caused by the incident X-ray beam. This produces both global and site-specific damage. Site specific damage can misdirect the biological interpretation of the structural models produced. Cryo-cooling crystals has be...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671560/ https://www.ncbi.nlm.nih.gov/pubmed/33201877 http://dx.doi.org/10.1371/journal.pone.0239702 |